薛挺

薛　挺薛挺，博士，特任副教授。2004至2009年就读于中国科学技术大学生命学院分子微生物实验室，获博士学位；随后留校从事博士后研究，博士后工作期间获中国博士后科学基金46批面上资助及第三批特别资助；2011年6月任生命科学学院特任副教授。主要从事金黄色葡萄球菌致病性调控的相关研究，研究成果发表于InfectionandImmunity,MedicalMicrobiologyandImmunology,CellResearch等国际学术期刊。主要研究兴趣：1.金黄色葡萄球菌的群体感应、二元信号系统及转录因子网络对致病性调控的分子机制；2.金黄色葡萄球菌中新型smallRNA的探寻及其与致病性相关的上下游调控通路；3.金黄色葡萄球菌与宿主相互作用的分子机制。代表性论文：1.T.Xue*,Y.You,D.Hong,H.Sun,andB.Sun*.StaphylococcusaureusKdpDEtwo-componentsystemcouplesextracellularK+sensingandAgrsignalingtoinfectionprogramming.InfectionandImmunity.(2011)79:2154-2167.2.T.Xue*φ,Y.Youφ,F.ShangandB.Sun*.RotandAgrsystemmodulatefibrinogen-bindingabilitymainlybyregulatingclfBexpressioninStaphylococcusaureusNCTC8325.MedicalMicrobiologyandImmunology.(2011)Inpress.(φco-1stauthor)3.T.Xue*φ,X.Zhangφ,andB.Sun*.QrrB,thenovelstaphylococalsmallRNA,couplesAgrquorumsensingtovirulenceregulation.(2011).Inpreparation.(φco-1stauthor)4.T.Xue,L.Zhao,H.Sun,X.Zhou,andB.Sun*.LsrRbinding-siterecognitionandregulatorycharacteristicsinEscherichiacoliAI-2quorumsensing.CellResearch.(2009)19:1258-1268.5.F.Shangφ,T.Xueφ,H.Sun,L.Xing,S.Zhang,Z.Yang,L.ZhangandB.Sun*.TheStaphylococcusaureusGGDEFprotein(GdpS)influencesproteinAgeneexpressioninac-di-GMPindependentmanner.InfectionandImmunity.(2009)77:2849-2856.（φco-1stauthor）6.L.Zhao,T.Xue,F.Shang,H.Sun,andB.Sun*.StaphylococcusaureusAI-2quorumsensingassociateswiththeKdpDEtwo-componentsystemtoregulatecapsularpolysaccharidesynthesisandvirulence.InfectionandImmunity.(2010)78:3506-3515.7.E.Fei,X.Ma,C.Zhu,T.Xue,J.Yan,Y.Xu,J.Zhou,andG.Wang*.Nucleocytoplasmicshuttlingofdysbindin-1,aschizophreniarelatedprotein,regulatessynapsinIexpression.TheJournalofbiologicalchemistry.(2010)285:38630-38640.8.Ma,J.,Z.Ren,Y.Ma,L.Xu,Y.Zhao,C.Zheng,Y.Fang,T.Xue,B.Sun,andW.Xiao*.TargetedknockdownofEGR-1inhibitsIL-8productionandIL-8-mediatedinvasionofprostatecancercellsthroughsuppressingEGR-1/NF-kappaBsynergy.TheJournalofbiologicalchemistry.(2009)284:34600-34606.9.X.Wang,S.Foday,T.Xue,andB.Sun*.Methylobacteriumsalsuginissp.nov.,is